Title

Could the Quick Inventory of Depressive Symptomatology-Self-Report (QIDS-SR) be used in depressed schizophrenia patients?

Publication Date

2014

Journal Title

J Affect Disord

Abstract

BACKGROUND: Developing accurate and time-efficient tools to measure depressive symptoms in schizophrenia is important for research and clinical practice. This study tested the psychometric properties of the Chinese version of the 16-item Quick Inventory of Depressive Symptomatology (QIDS-SR) in depressed schizophrenia patients. METHODS: This study included 337 clinically stable patients with schizophrenia. The severity of depressive symptoms was assessed using the Montgomery-Asberg Depression Rating Scale (MADRS), QIDS-SR at baseline and 2 weeks later. Negative symptoms and extrapyramidal symptoms were measured with the negative symptom score of Brief Psychiatric Rating Scale (BPRS) and the Simpson-Angus Scale of Extrapyramidal Symptoms (SAS), respectively. RESULTS: Internal consistency (Cronbachs alpha) was 0.73 and 0.67 for QIDS-SR at the baseline and endpoint, respectively. The intra-class correlation coefficient (ICC) for test-retest reliability over the two weeks was 0.77. Two domains (involvement and energy) at baseline and one domain (energy) at endpoint had the highest item-total correlations. The QIDS-SR total score was significantly correlated with the MADRS total score at baseline (r=0.44, p

Volume Number

172c

Pages

191-194

Document Type

Article

EPub Date

2014/12/03

Status

Faculty

Facility

School of Medicine

Primary Department

Psychiatry

Additional Departments

Molecular Medicine

PMID

25451417

DOI

10.1016/j.jad.2014.09.051