Title

Fetal and Postnatal Magnetic Resonance Imaging of Unilateral Cystic Renal Dysplasia in a Neonate with Tuberous Sclerosis

Publication Date

2014

Journal Title

Pediatr Neonatol

Abstract

Tuberous sclerosis (TS) is an autosomal dominant condition associated with mutations in the TSC1 and/or TSC2 genes. Clinical manifestations are multisystemic, and they often include lesions in the brain, skin, heart, kidneys, and bones. TSC2 gene mutations can be seen concomitantly with autosomal dominant polycystic kidney disease gene mutations. We present a case of a fetus with prenatal diagnosis of TS that had unique asymmetrical distribution of renal cystic disease. We describe the extensive work up with both fetal and neonatal magnetic resonance imaging with correlating images of the unilateral polycystic renal disease in addition to typical TS brain findings.

Volume Number

57

Issue Number

5

Pages

440-443

Document Type

Article

EPub Date

2014/02/06

Status

Northwell Researcher

Facility

Northwell Health

Primary Department

Obstetrics and Gynecology

PMID

24495558

DOI

10.1016/j.pedneo.2013.10.014