Publication Date

2014

Journal Title

Br J Cancer

Abstract

Background: Securing a diagnosis of ovarian cancer and establishing means to predict outcomes to therapeutics remain formidable clinical challenges. Early diagnosis is particularly important since survival rates are markedly improved if tumour is detected early. Methods: Comprehensive miRNA profiles were generated on presurgical plasma samples from 42 women with confirmed serous epithelial ovarian cancer, 36 women diagnosed with a benign neoplasm, and 23 comparably age-matched women with no known pelvic mass. Results: Twenty-two miRNAs were differentially expressed between healthy controls and the ovarian cancer group (P

Volume Number

110

Issue Number

4

Pages

976-983

Document Type

Article

EPub Date

2013/12/25

Status

Faculty; Northwell Researcher

Facility

School of Medicine; Northwell Health

Primary Department

Obstetrics and Gynecology

Additional Departments

Molecular Medicine

PMID

24366298

DOI

10.1038/bjc.2013.795


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