Publication Date

2014

Journal Title

Cell Signal

Abstract

In the present study, we evaluated the effect of short term hyperglycemia on renal lesions in a mouse model (Tg26) of HIV-associated nephropathy (HIVAN). Control and Tg26 mice in groups (n=6) were administered either normal saline (FVBN or Tg) or streptozotocin (FVBN+STZ or Tg26+STZ). After two weeks, biomarkers were collected and kidneys were harvested. FVBN+ STZ and Tg26+STZ displayed elevated serum glucose levels when compared to FVBN and Tg26 respectively. Tg26+STZ displayed elevated (P

Volume Number

27

Issue Number

3

Pages

460-469

Document Type

Article

EPub Date

2014/12/30

Status

Faculty; Northwell Resident

Facility

School of Medicine; Northwell Health

Primary Department

Medicine

PMID

25542307

DOI

10.1016/j.cellsig.2014.12.011


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