Title
Hypothalamic dysfunction without hamartomas causing gelastic seizures in optic nerve hypoplasia
Publication Date
2015
Journal Title
J Child Neurol
Abstract
This report describes gelastic seizures in patients with optic nerve hypoplasia and hypothalamic dysfunction without hypothalamic hamartoma. All participants (n = 4) from the optic nerve hypoplasia registry study at Children's Hospital Los Angeles presenting with gelastic seizures were included. The clinical and pathology characteristics include hypothalamic dysgenesis and dysfunction, but no hamartomas. Optic nerve hypoplasia is the only reported condition with gelastic seizures without hypothalamic hamartomas, suggesting that hypothalamic disorganization alone can cause gelastic seizures.
Volume Number
30
Issue Number
2
Pages
233-7
Document Type
Article
EPub Date
2014/04/05
Status
Northwell Researcher
Facility
Northwell Health
Primary Department
Ophthalmology
PMID
DOI
10.1177/0883073814527156