Title

New insights into Stargardt disease with multimodal imaging

Publication Date

2015

Journal Title

Ophthalmic Surg Lasers Imaging Retina

Abstract

A 20-year-old woman with bilateral mild blurring of vision presented with a bull's eye maculopathy and was diagnosed with Stargardt disease, confirmed with genetic testing. The authors present several novel multimodal imaging findings including multicolor and multi-spectral imaging that enhanced visualization of perifoveal flecks, fundus autofluorescence that revealed both perifoveal and perimacular rings of hyperautofluorescence, adaptive optics imaging that revealed unprecedented visualization of cones at the fovea due to decreased cone density, and spectral-domain optical coherence tomography that identified thickening and increased hyperreflectivity of the external limiting membrane as a possible transient biomarker of early Stargardt disease.

Volume Number

46

Issue Number

2

Pages

257-61

Document Type

Article

EPub Date

2015/02/24

Status

Northwell Researcher

Facility

Northwell Health

Primary Department

Ophthalmology

PMID

25707054

DOI

10.3928/23258160-20150213-09

Comments

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