Title

Self-Expanding Prostheses for Transcatheter Aortic Valve Replacement

Publication Date

January 2014

Journal Title

Progress in Cardiovascular Diseases

Abstract

Transcatheter aortic valve replacement (TAVR) has emerged as an alternative to surgical aortic valve replacement in patients who are considered high surgical risk or inoperable due to advanced age and comorbidities. Randomized trial and registry data have demonstrated the safety and efficacy of TAVR in such patients. Currently available transcatheter heart valves (THVs) employ either balloon-expandable or self-expanding designs, and several new designs have shown promising early results. Differences in valve design may offer specific advantages for accurate deployment and minimizing complications. This article reviews several designs of self-expanding THVs that are currently available or have undergone successful implantation in humans. Additional studies are required to compare the relative performance of these devices. (C) 2014 Elsevier Inc. All rights reserved.

Volume Number

56

Issue Number

6

Pages

596-609

Document Type

Article

EPub Date

2014/05/20

Facility

School of Medicine

Primary Department

Pediatrics

Additional Departments

Cardiology; Cardiovascular and Thoracic Surgery

PMID

WOS:000336469800005

DOI

10.1016/j.pcad.2014.03.002

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