Title

Articulating Vs. Static Antibiotic Impregnated Spacers in Revision Total Knee Arthroplasty for Sepsis. A Systematic Review

Publication Date

2014

Journal Title

J Arthroplasty

Abstract

Periprosthetic infection after total knee arthroplasty is a devastating complication, and two-stage exchange is the standard of care in North America. Articulating and static spacers have been developed to treat these infections but controversy exists over which method is superior. We performed a systematic review using MEDLINE and other literature search engines identifying 47 articles meeting inclusion criteria producing 2011 spacers for comparison. Articulating spacers had increased range of motion 100.1 degrees vs. 82.9 degrees (P < 0.003), lower re-infection rate 7.5% (P < 0.0031), facilitated re-implantation (P < 0.0011), and developed less bone loss (P < .0001) than did static spacers. This study answers several clinically relevant questions and provides useful information in guiding clinical decision making in treating periprosthetic infection. (C) 2014 Elsevier Inc. All rights reserved.

Volume Number

29

Issue Number

3

Pages

558-563

Document Type

Article

Status

Faculty

Facility

School of Medicine

Primary Department

Orthopedic Surgery

PMID

24268975

DOI

10.1016/j.arth.2013.08.013