Title

Diagnosis and Staging of Medication-Related Osteonecrosis of the Jaw

Publication Date

2015

Journal Title

Oral Maxillofac Surg Clin North Am

Abstract

The relationship between osteonecrosis of the jaw and bisphosphonate therapy was initially established more than 10 years ago. Since that time our understanding of this disease process has evolved as the direct result of clinical, basic science, and animal research initiatives. Medication-related osteonecrosis of the jaw (MRONJ) is a well-known entity now known to be associated with various antiresorptive therapies and recently with antiangiogenic medications. This article reviews the recently modified diagnostic criteria for MRONJ with a focus on the clinical, histopathologic, and imaging characteristics of this disease process.

Volume Number

27

Issue Number

4

Pages

479-87

Document Type

Article

EPub Date

2015/08/22

Status

Faculty

Facility

School of Medicine

Primary Department

Dental Medicine

PMID

26293329

DOI

10.1016/j.coms.2015.06.008