Title
Diagnosis and Staging of Medication-Related Osteonecrosis of the Jaw
Publication Date
2015
Journal Title
Oral Maxillofac Surg Clin North Am
Abstract
The relationship between osteonecrosis of the jaw and bisphosphonate therapy was initially established more than 10 years ago. Since that time our understanding of this disease process has evolved as the direct result of clinical, basic science, and animal research initiatives. Medication-related osteonecrosis of the jaw (MRONJ) is a well-known entity now known to be associated with various antiresorptive therapies and recently with antiangiogenic medications. This article reviews the recently modified diagnostic criteria for MRONJ with a focus on the clinical, histopathologic, and imaging characteristics of this disease process.
Volume Number
27
Issue Number
4
Pages
479-87
Document Type
Article
EPub Date
2015/08/22
Status
Faculty
Facility
School of Medicine
Primary Department
Dental Medicine
PMID
DOI
10.1016/j.coms.2015.06.008