Title
Is there a need for an alternative in the era of novel anticoagulants?
Publication Date
2015
Journal Title
Expert Rev Cardiovasc Ther
Abstract
With the development of the new direct oral anticoagulants, many of the unmet needs of the vitamin K antagonists were fulfilled, such as the absence of dietary interactions, few drug interactions, predictable effects and no need for monitoring. However, growing experience with the direct oral anticoagulants indicates there is still room for improvement. Developing antithrombotic agents that optimize their antithrombotic effect while producing little or no risk of bleeding is a long sought after goal. This and other enhanced attributes of candidate drugs are on the horizon.
Volume Number
13
Issue Number
9
Pages
967-70
Document Type
Article
EPub Date
2015/07/21
Status
Faculty
Facility
School of Medicine
Primary Department
General Internal Medicine
PMID
DOI
10.1586/14779072.2015.1069707