Title
Obstructive Sleep Apnea An Unexpected Cause of Insulin Resistance and Diabetes
Publication Date
2014
Journal Title
Endocrinol Metabol Clin North Am
Abstract
Obstructive sleep apnea (OSA) is prevalent with type 2 diabetes. Conversely, nondiabetic patients with OSA are at increased risk of developing insulin resistance and diabetes. These disorders independently contribute to increased cardiovascular and cerebrovascular morbidity and mortality. The pathophysiology of OSA may help explain these associations. Evidence demonstrates that treatment of OSA with continuous positive airway pressure may lead to improvement in insulin sensitivity, hemoglobin A1c, systemic hypertension, and other components of the metabolic syndrome. Recognizing and treating OSA in patients with insulin resistance or diabetes ameliorates OSA-related symptoms and improves cardiometabolic risk.
Volume Number
43
Issue Number
1
Pages
187-204
Document Type
Article
EPub Date
2014/03/04
Status
Faculty; Northwell Researcher
Facility
School of Medicine; Northwell Health
Primary Department
Pulmonary, Critical Care, and Sleep Medicine
PMID
DOI
10.1016/j.ecl.2013.09.002