Beyond Reflux: Risk Factors for UTI Recurrence and Scarring
AAP Grand Rounds
Keren R, Shaikh N, Pohl H, et al. Risk factors for recurrent urinary tract infection and renal scarring. Pediatrics. 2015; 136( 1): e13– e21; doi:10.1542/peds.2015-0409OpenUrlAbstract/FREE Full TextKey wordsurinary tract infectionvoiding dysfunctionvesicoureteral refluxPICOQuestion: Among children aged 2–71 months with and without vesicoureteral reflux, what factors are associated with increased risk of urinary tract infection recurrence and renal scarring?Question type: PrognosisStudy type: Prospective cohortInvestigators from multiple institutions conducted a 2-year prospective cohort study of children with a history of urinary tract infection (UTI) with and without vesicoureteral reflux (VUR) in order to identify risk factors for recurrent UTI and renal scarring. Two cohorts of children were enrolled. The first cohort were children with grade I–IV VUR who were randomized to placebo (no antibiotic prophylaxis) in the RIVUR study (Randomized Intervention for …
School of Medicine
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