Title
The Genotype and Phenotype (GaP) registry: a living biobank for the analysis of quantitative traits
Publication Date
2015
Journal Title
Immunol Res
Abstract
We describe the development of the Genotype and Phenotype (GaP) Registry, a living biobank of normal volunteers who are genotyped for genetic markers related to human disease. Participants in the GaP can be recalled for hypothesis driven study of disease associated genetic variants. The GaP has facilitated functional studies of several autoimmune disease associated loci including Csk, Blk, PDRM1 (Blimp-1) and PTPN22. It is likely that expansion of such living biobank registries will play an important role in studying and understanding the function of disease associated alleles in complex disease.
Volume Number
63
Issue Number
1-3
Pages
107-12
Document Type
Article
EPub Date
2015/10/16
Status
Faculty; Northwell Researcher
Facility
School of Medicine; Northwell Health
Primary Department
Molecular Medicine
Additional Departments
General Internal Medicine
PMID
DOI
10.1007/s12026-015-8711-8