Title
Age-associated B cells acquire a new wrinkle news-and-views
Publication Date
2018
Journal Title
Nat Immunol
Abstract
© 2018 The Author(s). SWAP-70 and DEF6 prevent the cytokine IL-21-induced transcription factor IRF5 from binding to DNA and recruiting the transcription factor T-bet and thereby diminish the activation of age-associated B cells.
Volume Number
19
Issue Number
4
Pages
317 - 318
Document Type
Article
Status
Faculty; Northwell Researcher
Facility
School of Medicine; Northwell Health
Primary Department
Molecular Medicine
Additional Departments
General Internal Medicine
PMID
DOI
10.1038/s41590-018-0072-8