Title

Dissociated Oxygen Consumption and Carbon Dioxide Production in the Post-Cardiac Arrest Rat: A Novel Metabolic Phenotype.

Authors

K. Shinozaki, Northwell Health
L. Becker, Zucker School of Medicine at Hofstra/NorthwellFollow
Kota Saeki
J. Kim, Zucker School of Medicine at Hofstra/NorthwellFollow
T. Yin, Northwell Health
Tong Da
J. W. Lampe, Zucker School of Medicine at Hofstra/NorthwellFollow

Publication Date

2018

Journal Title

J Am Heart Assoc

Abstract

BACKGROUND: The concept that resuscitation from cardiac arrest (CA) results in a metabolic injury is broadly accepted, yet patients never receive this diagnosis. We sought to find evidence of metabolic injuries after CA by measuring O

METHODS AND RESULTS: Rats were anesthetized and randomized into 3 groups: resuscitation from 10-minute asphyxia with inhaled 100% O

CONCLUSIONS: CA altered cellular metabolism resulting in increased VO

Volume Number

7

Issue Number

13

Document Type

Article

Status

Faculty; Northwell Researcher; Northwell Resident

Facility

School of Medicine; Northwell Health

Primary Department

Molecular Medicine

Additional Departments

Emergency Medicine

PMID

29959138

DOI

10.1161/JAHA.117.007721