Stillbirth during infection with middle east respiratory syndrome coronavirus

D. C. Payne
I. Iblan
S. Alqasrawi
M. Al Nsour
B. Rha
R. A. Tohme
G. R. Abedi
N. H. Farag
A. Haddadin
T. T. Al Sanhouri
N. Jarour
D. L. Swerdlow
D. J. Jamieson
M. A. Pallansch
L. M. Haynes
S I. Gerber
M. M. Al Abdallat
N. Sabri
M. Al Azhari
D. Kuhar

Abstract

We conducted an epidemiologic investigation among survivors of an outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in Jordan. A second-trimester stillbirth occurred during the course of an acute respiratory illness that was attributed to MERS-CoV on the basis of exposure history and positive results of MERS-CoV serologic testing. This is the first occurrence of stillbirth during an infection with MERS-CoV and may have bearing upon the surveillance and management of pregnant women in settings of unexplained respiratory illness potentially due to MERS-CoV. Future prospective investigations of MERS-CoV should ascertain pregnancy status and obtain further pregnancy-related data, including biological specimens for confirmatory testing. © 2014 The Author 2014.