Use of Pulmonary Artery Pulsatility Index in Cardiac Surgery.
J Cardiothorac Vasc Anesth
OBJECTIVE: This study evaluated whether the pulmonary artery pulsatility index (PAPi) collected before and after cardiopulmonary bypass (CPB) is predictive and diagnostic of new onset right ventricular (RV) failure in the elective cardiac surgical population.
DESIGN: This was a prospective observational study of patients who underwent cardiac surgery between 2017 and 2019.
SETTING: Weill Cornell Medicine, a single large academic medical center.
PARTICIPANTS: The study comprised 119 patients undergoing elective cardiac surgery.
INTERVENTIONS: Cardiopulmonary bypass, transesophageal echocardiography, pulmonary artery catheter, and elective cardiac surgery.
MEASUREMENTS AND MAIN RESULTS: Echocardiographic and hemodynamic data were collected at 2 time points: pre-CPB and post-chest closure/post-CPB. Patients with and without post-CPB RV dysfunction fractional area of change (
CONCLUSIONS: PAPi measured pre-CPB is a potential predictor and marker of post-CPB RV dysfunction and may have diagnostic utility in cardiac surgery. Additional, large-scale studies are needed to confirm this finding.
School of Medicine