Incidence of Thrombotic Events and Outcomes in COVID-19 Patients Admitted to Intensive Care Units.

A. Avula, Northwell Health
K. Nalleballe
S. Toom
S. Siddamreddy
D. Gurala, Northwell Health
N. Katyal
S. Maddika
A. D. Polavarapu, Northwell Health
R. Sharma
S. Onteddu

Abstract

Introduction While coronavirus disease 2019 (COVID-19) mostly causes respiratory illnesses, emerging evidence has shown that patients with severe COVID-19 can develop complications like venous thromboembolism (VTE) and arterial thrombosis as well. The incidence of thrombosis among critically ill patients in the literature has been highly variable, ranging from 25 to 69%. Similarly, reported mortality among critically ill patients has been highly variable too, and it has ranged from 30 to 97%. In this study, we analyzed data from a large database to address the incidence, the risk factors leading to thrombotic complications, and mortality rates among COVID-19 patients. Material and methods Data were obtained from TriNetX (TriNetX, Inc., Cambridge, MA), a multinational clinical research platform that collects medical records from 42 healthcare organizations (HCOs). All nominal data were compared using the chi-squared test. Alpha of