Title
Similarities and Differences Between Nonalcoholic Steatohepatitis and Other Causes of Cirrhosis
Publication Date
2020
Journal Title
Gastroenterol Clin North Am
Abstract
© 2019 Elsevier Inc. Nonalcoholic fatty liver disease includes a spectrum of liver disorders that range from simple steatosis to nonalcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. Risk factors such as obesity, hypertension, hyperlipidemia, chronic kidney disease, and smoking status increase risk of progression to cirrhosis among patients with NASH. Cirrhosis derived from non-NASH causes may share similar features with patients with NASH but embody distinct pathogenetic mechanisms, genetic associations, prognosis, and outcomes. This article discusses in detail the comparison of clinical, genetic, and outcome characteristics between patients with NASH cirrhosis as opposed to alternative causes of chronic liver disease.
Volume Number
49
Issue Number
1
Pages
151 - 164
Document Type
Article
Status
Faculty
Facility
School of Medicine
Primary Department
Hepatology
PMID
DOI
10.1016/j.gtc.2019.09.004