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Submissions from 2018

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Association between psychosis in elderly patients with Alzheimer disease and impaired social cognition, J. Koppel, A. Sousa, M. L. Gordon, L. Giliberto, E. Christen, and P. Davies

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Corrected and Republished from: The COP9 Signalosome Interacts with and Regulates Interferon Regulatory Factor 5 Protein Stability., J. Korczeniewska and B. J. Barnes

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Obesity/Bariatric Surgery and Crohn's Disease, B. I. Korelitz, N. Sonpal, J. Schneider, A. Swaminath, J. Felder, M. Roslin, and J. Aronoff

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High-Frequency Percussive Ventilation Rescue Therapy in Morbidly Obese Patients Failing Conventional Mechanical Ventilation., A. Korzhuk, A. Afzal, I. Wong, F. Khusid, B. Worku, and I. Gulkarov

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CT Imaging of Emergent Renal Conditions, K. Kothari and J. J. Hines

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Longitudinal evaluation of diffusion tensor imaging and cognition in systemic lupus erythematosus, E. Kozora, C. M. Filley, D. Erkan, A. M. Uluğ, A. Vo, G. Ramon, A. Burleson, R. D. Zimmerman, and M. D. Lockshin

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Improving the Power of the American Society of Anesthesiology Classification System to Risk Stratify Vascular Surgery Patients Based on National Surgical Quality Improvement Project–Defined Functional Status, A. I. Kraev, J. McGinn, Y. Etkin, J. W. Turner, and G. S. Landis

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Mesalamine Associated Bradycardia., M. Krzyzak, A. Gupta, E. Antonov, and S. M. Mulrooney

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Anticholinergic Toxicity Secondary to Overuse of Topricin Cream, a Homeopathic Medication., M. Krzyzak, A. Regina, R. C. Jesin, L. Deeb, E. Steinberg, and N. Majlesi

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Cyclical cardiorenal syndrome in late-stage kidney disease, B. Ku and S. Fishbane

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Intracranial electrophysiology reveals reproducible intrinsic functional connectivity within human brain networks, A. Kucyi, J. Schrouff, S. Bickel, B. L. Foster, J. M. Shine, and J. Parvizi

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The relationship between in-session commitment language and daily self-reported commitment to reduce or abstain from drinking, A. Kuerbis, J. Houser, P. Amrhein, H. Treloar Padovano, and J. Morgenstern

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Exploration of treatment matching of problem drinker characteristics to motivational interviewing and non-directive client-centered psychotherapy, A. Kuerbis, J. Houser, S. Levak, S. Shao, and J. Morgenstern

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Comparing daily drivers of problem drinking among older and younger adults: An electronic daily diary study using smartphones, A. Kuerbis, H. Treloar Padovano, S. Shao, J. Houser, F. J. Muench, and J. Morgenstern

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Financial planning and satisfaction across life domains among retired emergency physicians in the United States, G. J. Kuhn, C. A. Marco, M. N. Mallory, M. Blanda, J. A. Kaplan, S. M. Schneider, K. B. Joldersma, S. I. Martin, and E. K. Choo

superselective intraarterial cerebral infusion of cetuximab with blood brain barrier disruption combined with stupp protocol for newly diagnosed glioblastoma, K. O. Kulason, S. Chakraborty, C. G. Filippi, B. Pramanik, S. Fralin, K. Tan, A. Ray, R. Ortiz, A. Demopoulos, D. J. Langer, J. A. Boockvar, and +3 additional authors

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Lesional Temporal Lobe Epilepsy: Beware the Deceitful "Panic Attack", K. O. Kulason, J. R. Schneider, R. Rahme, B. Pramanik, D. Chong, and J. A. Boockvar

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Aortic root fibroelastoma causing cardiac ischemia, S. Kumar, R. Zeltser, and A. N. Makaryus

Role of Apolipoprotein L1 in Human Parietal Epithelial Cell Transition., V. Kumar, H. Vashistha, X. Lan, N. Chandel, K. Ayasolla, S. S.M. Shoshtari, R. Aslam, N. Paliwal, A. Malhotra, P. C. Singhal, and +7 additional authors

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Inflammatory chemokine eotaxin-1 is correlated with age in heroin dependent patients under methadone maintenance therapy, H. W. Kuo, T. H. Liu, H. H. Tsou, Y. T. Hsu, S. C. Wang, C. P. Fang, C. C. Liu, A. C. Chen, and Y. L. Liu

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The effect of fecal microbiota transplantation on psychiatric symptoms among patients with irritable bowel syndrome, functional diarrhea and functional constipation: An open-label observational study, S. Kurokawa, T. Kishimoto, S. Mizuno, T. Masaoka, M. Naganuma, K. C. Liang, M. Kitazawa, M. Nakashima, C. Shindo, M. Mimura, and +3 additional authors

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Comparing phospholipid profiles of mitochondria and whole tissue: Higher PUFA content in mitochondria is driven by increased phosphatidylcholine unsaturation, C. E. Kuschner, J. Choi, T. Yin, K. Shinozaki, L. B. Becker, J. W. Lampe, and J. Kim

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Epilepsy surgery in Panama: Establishment of a successful hybrid program as a model for small middle-income countries., R. Kuzniecky, C. Baez, G. Aranda, E. T. Hidalgo, A. Grover, C. Orillac, Zelenka, and H. L. Weiner

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Local Immunotherapy for Malignancy: A Role for Brain Tumors?, K. Kwan, L. Falting, J. R. Schneider, and J. A. Boockvar

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Quality of Life in Patients With Glioblastoma Treated With Tumor-Treating Fields, K. Kwan, J. R. Schneider, and J. A. Boockvar

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Lessons Learned Using a High-Definition 3-Dimensional Exoscope for Spinal Surgery., K. Kwan, J. R. Schneider, V. Du, L. Falting, J. A. Boockvar, J. Oren, M. Levine, and D. J. Langer

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Targeting Epidermal Growth Factor Receptors in Recurrent Glioblastoma Via a Novel Epithelial Growth Factor Receptor-Conjugated Nanocell Doxorubicin Delivery System, K. Kwan, J. R. Schneider, A. Kobets, and J. A. Boockvar

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Response to Perrella et al, P. Y. Kwo, M. L. Shiffman, and D. E. Bernstein

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The cochrane review conclusion for Hepatitis C DAA therapies is wrong, P. Y. Kwo, M. L. Shiff, and D. E. Bernstein

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A primary breast cancer with distinct foci of estrogen receptor-alpha positive and negative cells derived from the same clonal origin as revealed by whole exome sequencing, K. Kyker-Snowman, B. Erlanger Avigdor, M. Nasim, A. Cimino-Mathews, S. J. Wheelan, P. Argani, and B. H. Park

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Comorbidity of chronic somatic diseases in patients with psychotic disorders and their influence on 4-year outcomes of integrated care treatment (ACCESS II study), M. Lambert, F. Ruppelt, A. Siem, A. C. Rohenkohl, V. Kraft, D. Luedecke, M. Sengutta, R. Schroeter, C. U. Correll, D. Schoettle, and +4 additional authors

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Early detection and integrated care for adolescents and young adults with severe psychotic disorders: rationales and design of the Integrated Care in Early Psychosis Study (ACCESS III), M. Lambert, D. Schoettle, M. Sengutta, F. Ruppelt, A. Rohenkohl, D. Luedecke, L. A. Nawara, B. Galling, C. U. Correll, A. Karow, and +22 additional authors

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Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018), M. Lam, J. W. Trampush, J. Yu, E. Knowles, S. Djurovic, I. Melle, K. Sundet, P. DeRosse, A. K. Malhotra, T. Lencz, and +51 additional authors

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Effect of compression waveform and resuscitation duration on blood flow and pressure in swine: One waveform does not optimally serve, J. W. Lampe, T. Yin, G. Bratinov, C. L. Kaufman, R. A. Berg, A. Venema, and L. B. Becker

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Cpx-351 (cytarabine and daunorubicin) liposome for injection versus conventional cytarabine plus daunorubicin in older patients with newly diagnosed secondary acute myeloid leukemia, J. E. Lancet, G. L. Uy, J. E. Cortes, L. F. Newell, T. L. Lin, E. K. Ritchie, R. K. Stuart, S. A. Strickland, J. E. Kolitz, B. C. Medeiros, and +11 additional authors

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End-Tidal Carbon Dioxide Use for Tracheal Intubation: Analysis from the National Emergency Airway Registry for Children (NEAR4KIDS) Registry, M. L. Langhan, B. L. Emerson, S. Nett, M. Pinto, I. Harwayne-Gidansky, K. J. Rehder, C. Krawiec, K. Meyer, S. Gangadharan, A. Nishisaki, and +10 additional authors

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Nicotine enhances mesangial cell proliferation and fibronectin production in high glucose milieu via activation of Wnt/beta-catenin pathway, X. Lan, H. Wen, R. Aslam, S. S. Shoshtari, A. Mishra, V. Kumar, H. Wang, G. Wu, A. Malhotra, P. C. Singhal, and +1 additional author

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Huntingtin-interacting protein 1 (HIP1) regulates arthritis severity and synovial fibroblast invasiveness by altering PDGFR and Rac1 signalling, T. Laragione, M. Brenner, A. Lahiri, E. Gao, C. Harris, and P. S. Gulko

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The pharmacological management of metabolic syndrome, J. R. Larsen, L. Dima, C. U. Correll, and P. Manu

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Pre-close technique of percutaneous closure for delayed hemostasis of large-bore femoral sheaths, K. Lata, A. Kaki, C. Grines, N. Blank, M. Elder, and T. Schreiber

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Day-case surgery is possible in the majority of men undergoing transurethral resection of the prostate – a report on over 1000 cases, L. Lavan, G. Kyriazis, D. Mbiabjeu, R. Gormley, S. Hall, R. Robinson, and D. Hodgson

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Baseline Characteristics of the Vitamin D and Type 2 Diabetes (D2d) Study: A Contemporary Prediabetes Cohort That Will Inform Diabetes Prevention Efforts, E. S. LeBlanc, R. E. Pratley, B. Dawson-Hughes, M. A. Staten, P. R. Sheehan, M. R. Lewis, A. Peters, S. H. Kim, E. P. Liao, A. G. Pittas, and +16 additional authors

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Spontaneous coronary artery dissection (SCAD): The underdiagnosed cardiac condition that plagues women, S. Lebrun and R. M. Bond

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Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals, J. J. Lee, R. Wedow, A. Okbay, E. Kong, O. Maghzian, M. Zacher, A. N. Tuan, T. Lencz, A. K. Malhotra, D. Cesarini, and +67 additional authors

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Multicenter Registry of Real-World Patients with Severely Calcified Coronary Lesions Undergoing Orbital Atherectomy: 1-Year Outcomes, M. S. Lee, E. Shlofmitz, A. Goldberg, and R. Shlofmitz

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Impact of the Use of Intravascular Imaging on Patients Who Underwent Orbital Atherectomy, M. S. Lee, E. Shlofmitz, J. Kong, G. Lluri, P. K. Srivastava, and R. Shlofmitz

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Outcomes of patients with severely calcified aorto-ostial coronary lesions who underwent orbital atherectomy, M. S. Lee, E. Shlofmitz, J. Kong, P. K. Srivastava, S. Al Yaseen, F. A. Sosa, M. Gallant, and R. Shlofmitz

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One-Year Outcomes of Orbital Atherectomy of Long, Diffusely Calcified Coronary Artery Lesions, M. S. Lee, E. Shlofmitz, G. Lluri, K. W. Park, J. Hollowed, and R. Shlofmitz

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Orbital Atherectomy of Severely Calcified Unprotected Left Main Coronary Artery Disease: One-Year Outcomes, M. S. Lee, E. Shlofmitz, K. W. Park, A. Goldberg, A. Jeremias, and R. Schlofmitz

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Outcomes of orbital atherectomy in severely calcified small (2.5 mm) coronary artery vessels, M. S. Lee, E. Shlofmitz, and R. Shlofmitz

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Procedural and long-term ischemic outcomes of tight subtotal occlusions treated with orbital atherectomy: An ORBIT II subanalysis., M. S. Lee, R. A. Shlofmitz, E. Shlofmitz, A. N. Behrens, G. Revtyak, B. J. Martinsen, and J. W. Chambers

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Orbital atherectomy for the treatment of small (2.5 mm) severely calcified coronary lesions: ORBIT II sub-analysis, M. S. Lee, R. A. Shlofmitz, E. Shlofmitz, P. K. Srivastava, J. Kong, C. Grines, G. Revytak, and J. W. Chambers

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The Role of Objectively Measured, Altered Physical Activity Patterns for Body Mass Index Change during Inpatient Treatment in Female Patients with Anorexia Nervosa, C. S. Lehmann, T. Hofmann, U. Elbelt, M. Rose, C. U. Correll, A. Stengel, and V. Haas

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American views of Sir Victor Horsley in the era of Cushing., K. R. Lehner and M. Schulder

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Reply to: Fluid Responsiveness: Goal-Directed Care or Resuscitative Guide to Salt Water Drowning?, D. E. Leisman, M. E. Doerfler, S. M. Schneider, J. A. D'Amore, and J. K. D'Angelo

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Predictors, Prevalence, and Outcomes of Early Crystalloid Responsiveness Among Initially Hypotensive Patients With Sepsis and Septic Shock, D. E. Leisman, M. E. Doerfler, S. M. Schneider, K. D. Masick, J. A. D'Amore, and J. K. D'Angelo

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High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation, T. Lencz, J. Yu, C. Palmer, S. Carmi, D. Ben-Avraham, N. Barzilai, S. Bressman, A. Darvasi, J. H. Cho, I. Pe'er, and +10 additional authors

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Palliative Care in New York State Nursing Homes: A Descriptive Study, P. E. Lester, F. Kawai, L. Rodrigues, J. Lolis, D. Martins-Welch, A. Shalshin, M. J. Fazzari, and C. X. Pan

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Activity restriction and risk of preterm delivery, H. I. Levin, A. Sciscione, C. V. Ananth, D. Drassinower, S. G. Obican, and R. J. Wapner

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A case of primary squamous cell carcinoma of the gallbladder with local invasion of the liver and peritoneum, and metastasis to the omentum., A. C.J. Levy, F. Casalduc-Coca, S. Asiry, and A. Goodman

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Nimodipine for the treatment of otolaryngic indications, Z. D. Levy, H. Shafeeq, and J. H. Sin

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Histopathologic characteristics of biopsies from dogs undergoing surgery with concurrent gross splenic and hepatic masses: 125 cases (2012-2016), F. J. Leyva, C. A. Loughin, C. W. Dewey, D. J. Marino, M. Akerman, and M. L. Lesser

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Correction to: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma, L. M. Liau, K. Ashkan, D. D. Tran, J. L. Campian, J. E. Trusheim, C. S. Cobbs, J. A. Heth, M. Salacz, M. Schulder, M. L. Bosch, and +59 additional authors

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First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma, L. M. Liau, K. Ashkan, D. D. Tran, J. L. Campian, J. E. Trusheim, C. S. Cobbs, J. A. Heth, M. Salacz, M. Schulder, M. L. Bosch, and +59 additional authors

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Identifying Advanced Illness Patients in the Emergency Department and Having Goals-of-Care Discussions to Assist with Early Hospice Referral, T. Liberman, A. Kozikowski, N. Kwon, B. Emmert, M. Akerman, and R. Pekmezaris

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The development of a Biobank of cancer tissue samples from World Trade Center responders, W. Lieberman-Cribbin, S. Tuminello, C. Gillezeau, M. Van Gerwen, R. Brody, M. Donovan, and E. Taioli

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Controversies and Challenges of Ventricular Assist Device Therapy, B. Lima, A. Bansal, J. Abraham, J. D. Rich, S. S. Lee, B. Soleimani, J. N. Katz, A. Kilic, J. S. Young, S. M. Joseph, and +1 additional author

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The impact of unfractionated heparin or bivalirudin on patients with stable coronary artery disease undergoing percutaneous coronary intervention, F. V. Lima, L. Gruberg, U. Aslam, M. Ramgadoo, K. Clase, A. Trevisan, and A. Jeremias

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Left ventricular end diastolic pressure and contrast-induced acute kidney injury in patients with acute coronary syndrome undergoing percutaneous coronary intervention, F. V. Lima, S. Singh, P. B. Parikh, and L. Gruberg

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Therapeutic Approaches to Secondary Fracture Prevention in High Risk Populations: Current Recommendations and Advances, H. Lim, M. Chamblain, B. Wong, and S. Raghavan

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Risk Factors for the Development of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis, Including Genetics, H. W. Lim and D. E. Bernstein

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An elderly patient's complete response to steroid therapy for collagenous gastritis, H. Lim, B. Y. Wong, D. Elkowitz, and K. Sultan

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Is 30-Day Posthospitalization Mortality Lower Among Racial/Ethnic Minorities?: A Reexamination, M. Lin, N. R. Kressin, M. K. Paasche-Orlow, E. J. Kim, L. Lopez, J. E. Rosen, and A. D. Hanchate

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Identification of ethyl pyruvate as a NLRP3 inflammasome inhibitor that preserves mitochondrial integrity, S. Li, F. Liang, K. Kwan, Y. Tang, X. Wang, Y. Tang, H. Yang, S. S. Chavan, H. Wang, K. J. Tracey, and +3 additional authors

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Glucocorticoid use and factors associated with variability in this use in the Systemic Lupus International Collaborating Clinics Inception Cohort, J. Little, B. Parker, M. Lunt, J. G. Hanly, M. B. Urowitz, A. E. Clarke, J. Romero-Diaz, C. Aranow, M. Mackay, I. N. Bruce, and +32 additional authors

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Transcatheter aortic valve replacement in patients with severe mitral or tricuspid regurgitation at extreme risk for surgery, S. H. Little, J. J. Popma, N. S. Kleiman, G. M. Deeb, T. G. Gleason, S. J. Yakubov, S. Checuti, A. Hartman, S. Katz, M. J. Reardon, and +11 additional authors

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Overexpression of β1 integrin contributes to polarity reversal and a poor prognosis of breast invasive micropapillary carcinoma, B. Liu, X. Zheng, F. Meng, Y. Han, Y. Song, F. Liu, S. Li, L. Zhang, X. Zhang, L. Fu, and +1 additional author

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APBB2 is associated with amphetamine use and plasma beta-amyloids in patients receiving methadone maintenance treatment, C. C. Liu, C. P. Fang, T. H. Liu, H. W. Kuo, S. C. Liu, S. C. Wang, A. C. Chen, and Y. L. Liu

Return to Work After Anatomic Total Shoulder Arthroplasty for Patients 55 Years and Younger at Average 5-Year Follow-up., J. N. Liu, G. H. Garcia, A. C. Wong, A. Sinatro, H. H. Wu, D. M. Dines, R. F. Warren, and L. V. Gulotta

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Return to sport after shoulder arthroplasty: a systematic review and meta-analysis, J. N. Liu, M. E. Steinhaus, G. H. Garcia, B. Chang, K. Fields, D. M. Dines, R. F. Warren, and L. V. Gulotta

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HO-1hipatrolling monocytes protect against vaso-occlusion in sickle cell disease, Y. Liu, F. Jing, W. Yi, A. Mendelson, P. Shi, R. Walsh, D. F. Friedman, C. Minniti, D. Manwani, K. Yazdanbakhsh, and +1 additional author

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Phosphoglycerate mutase 1 is highly expressed in C6 glioma cells and human astrocytoma, Z. Liu, J. Ding, C. Du, N. Xu, E. Wang, J. Li, Y. Wang, and J. Yu

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Connexin 43 Hemichannel as a Novel Mediator of Sterile and Infectious Inflammatory Diseases, W. Li, W. Chen, S. Zhu, M. He, G. Ma, Y. Al-Abed, H. Yang, K. J. Tracey, P. Wang, J. D'Angelo, H. Wang, and +4 additional authors

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Precise pathologic diagnosis and individualized treatment improve the outcomes of invasive micropapillary carcinoma of the breast: A 12-year prospective clinical study, W. Li, Y. Han, C. Wang, X. Guo, B. Shen, F. Liu, C. Jiang, Y. Li, X. Zhang, L. Fu, and +7 additional authors

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Lung epithelial cell-derived IL-25 negatively regulates LPS-induced exosome release from macrophages, Z. G. Li, M. J. Scott, T. Brzóska, P. Sundd, Y. H. Li, T. R. Billiar, M. A. Wilson, P. Wang, and J. Fan

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Focused update of expert consensus statement: Use of invasive assessments of coronary physiology and structure: A position statement of the society of cardiac angiography and interventions, A. Lotfi, J. E. Davies, W. F. Fearon, C. L. Grines, M. J. Kern, and L. W. Klein

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Case series supporting heme detoxification via therapeutic plasma exchange in acute multiorgan failure syndrome resistant to red blood cell exchange in sickle cell disease, J. E. Louie, C. J. Anderson, K. Fayaz M. Fomani, A. Henry, T. Killeen, N. Mohandas, K. Yazdanbakhsh, J. D. Belcher, G. M. Vercellotti, and P. A. Shi

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ACR Appropriateness Criteria®Breast Implant Evaluation, A. P. Lourenco, L. Moy, P. Baron, A. D. Didwania, R. M. diFlorio, S. L. Heller, A. I. Holbrook, A. A. Lewin, N. S. Vincoff, M. S. Newell, and +6 additional authors

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Credentialing of hospitalists in ultrasound-guided bedside procedures: A position statement of the society of hospital medicine, B. P. Lucas, D. M. Tierney, T. P. Jensen, R. Dancel, J. Cho, M. El-Barbary, R. Franco-Sadud, N. J. Soni, P. Mayo, V. Tayal, and +25 additional authors

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Histone H3K36M mutation and trimethylation patterns in chondroblastoma., C. Lu, D. Ramirez, S. Hwang, A. Jungbluth, D. Frosina, P. Ntiamoah, J. Healey, G. Zhu, W. Chen, M. Hameed, and +1 additional author

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Dynamic Cleft Maxillary Orthopedics and Periosteoplasty, F. N. Lukash, L. B. Shikowitz-Behr, M. Schwartz, and F. Tuminelli

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Escalation of Immunosuppressive Therapy for Inflammatory Bowel Disease Is Not Associated With Adverse Outcomes After Infection With Clostridium difficile., D. J. Lukin, G. Lawlor, D. P. Hudesman, L. Durbin, J. E. Axelrad, M. Passi, K. Cavaliere, M. Loftus, A. Swaminath, IBD-ReMEdY Study, and +5 additional authors

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The Public Face of Rhinoplasty: Impact on Perceived Attractiveness and Personality., S. M. Lu, D. T. Hsu, A. D. Perry, L. S. Leipziger, A. K. Kasabian, S. P. Bartlett, C. H. Thorne, P. N. Broer, and N. Tanna

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Pharmacotherapy for Perinatal Depression, S. I. Lusskin, S. J. Khan, C. Ernst, S. Habib, M. E. Fersh, and E. S. Albertini

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Greater extracellular free-water in first-episode psychosis predicts better neurocognitive functioning, A. E. Lyall, O. Pasternak, D. G. Robinson, D. Newell, J. W. Trampush, J. A. Gallego, M. Fava, A. K. Malhotra, K. H. Karlsgodt, P. R. Szeszko, and +1 additional author

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Diagnostic criteria for idiopathic pulmonary fibrosis: a Fleischner Society White Paper, D. A. Lynch, N. Sverzellati, W. D. Travis, K. K. Brown, T. V. Colby, J. R. Galvin, J. G. Goldin, D. M. Hansell, S. Raoof, A. U. Wells, and +7 additional authors

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Reply to: Diagnostic criteria for idiopathic pulmonary fibrosis, D. A. Lynch, N. Sverzellati, W. D. Travis, T. V. Colby, Y. Inoue, A. G. Nicholson, S. Raoof, L. Richeldi, C J. Ryerson, and J. H. Ryu

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Author's Reply To: Diagnostic criteria for idiopathic pulmonary fibrosis, D. A. Lynch, N. Sverzellati, W. D. Travis, T. V. Colby, Y. Inoue, A. G. Nicholson, S. Raoof, L. Richeldi, C. J. Ryerson, and J. H. Ryu

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Establishing Surrogate Kidney Endpoints for Lupus Nephritis Clinical Trials: Development and Validation of a Novel Approach to Predict Future Kidney Outcomes., M. Mackay, M. Dall'Era, J. Fishbein, K. Kalunian, M. Lesser, J. Sanchez Guerrero, D. M. Levy, E. Silverman, M. Petri, B. H. Rovin, and +19 additional authors

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Mutations of recombinant aquaporin-4 antibody in the Fc domain can impair complement-dependent cellular cytotoxicity and transplacental transport, S. Mader, L. Brimberg, J. N. Soltys, J. L. Bennett, and B. Diamond