Title
Effects of varying serum glucose levels on F-18-FDG biodistribution
Publication Date
2015
Journal Title
Nucl Med Commun
Abstract
ObjectiveHyperglycemia has been shown to influence fluorine-18 fluorodeoxyglucose (F-18-FDG) uptake in tumor cells. Therefore, patients are instructed to fast for 6h, while maintaining serum glucose levels at an acceptable range. The study was performed to evaluate the effect of fasting blood glucose levels on the biodistribution of F-18-FDG in various tissues including the liver, heart, bone marrow, skeletal muscle, and tumors.Materials and methodsFingerstick fasting blood glucose is routinely measured on the morning of the procedure. The maximum standardized uptake value (SUVmax) in the right and left hepatic lobes, left ventricle, sacrum, thigh, and tumor was measured in 229 consecutive patients undergoing F-18-FDG PET/computed tomography for tumor. Patients were divided into three groups depending on their serum glucose levels: low (
Volume Number
36
Issue Number
7
Pages
717-721
Document Type
Article
Status
Faculty, Northwell Resident, Northwell Researcher
Facility
School of Medicine; Northwell Health
Primary Department
Radiology
Additional Departments
Orthopedic Surgery
PMID
DOI
10.1097/mnm.0000000000000319