Title

Clinical and laboratory issues associated with persistent low-level elevations of hCG in a female of childbearing age

Publication Date

2014

Journal Title

Clinica Chimica Acta

Abstract

Persistent low-level elevations of serum concentrations of hCG in a non-pregnant female of childbearing age were investigated by a number of laboratory techniques including heterophile blocking reagents, polyethylene glycol precipitation, serial dilutions and hCG measurements on several different instrument/reagent systems. The results of these studies indicated that this patient had immunoreactive hCG in her serum that was not the intact hCG molecule but primarily the free beta-hCG subunit. Differential diagnoses are discussed along with recommendation for continued surveillance of serum hCG concentrations. (C) 2013 Elsevier B.V. All rights reserved.

Volume Number

430

Pages

22-23

Document Type

Article

EPub Date

2014/01/01

Status

Faculty; Northwell Researcher

Facility

School of Medicine; Northwell Health

Primary Department

Pathology and Laboratory Medicine

Additional Departments

Obstetrics and Gynecology

PMID

24378284

DOI

10.1016/j.cca.2013.12.029