Publication Date
2015
Journal Title
Ann Pediatr Cardiol
Abstract
Mutations in PRKAG2 gene that regulates the gamma2 subunit of the adenosine monophosphate (AMP) dependent protein kinase have been associated with the development of atrioventricular (AV) accessory pathways, cardiac hypertrophy, and conduction system abnormalities. These patients can potentially be misdiagnosed as hypertrophic cardiomyopathy (HOCM) and/or Wolf-Parkinson White (WPW) syndrome due to similar clinical phenotype. Early recognition of this disease entity is very important as ablation of suspected accessory pathways is not effective and the natural history of the disease is very different from HOCM and WPW syndrome.
Volume Number
8
Issue Number
2
Pages
153-6
Document Type
Article
EPub Date
2015/06/19
Status
Faculty
Facility
School of Medicine
Primary Department
General Pediatrics
PMID
DOI
10.4103/0974-2069.154149