Title
Safety of a 1-Day Polyethylene Glycol 3350 Bowel Preparation for Colonoscopy in Children
Publication Date
2015
Journal Title
J Pediatr Gastroenterol Nutr
Abstract
OBJECTIVES: Electrolyte-free polyethylene glycol powder (PEG-3350) has been widely used for colonoscopy preparation (prep), however limited safety data on electrolyte changes exists with 1-day prep regimens. The primary aim of this study was to determine the proportion of patients with significant serum chemistry abnormalities pre- and at the time of colonoscopy. Secondary aims included evaluation of prep tolerance and bowel cleansing efficacy. METHODS: We performed a prospective descriptive observational study of pediatric patients scheduled for outpatient colonoscopy who received our standard 1-day, weight-based 4 g/kg PEG-3350 prep with a single stimulant laxative dose and had serum chemistry testing within 60 days prior to and at the time of colonoscopy. A standardized bowel cleanliness tool (Aronchick scale) was completed by the endoscopist. RESULTS: 155 patients had serum electrolytes data pre- and post-prep. Comparison of each patient's chemistries demonstrated statistical equivalence with the 1 exception of blood urea nitrogen levels (p = 0.56). Hypokalemia was detected post-prep in 37 subjects (24%), but none had a serum level below 3.3 mmol/L, which was deemed to be of no clinical significance. Five patients were hypoglycemic post-prep; 3 were
Volume Number
63
Issue Number
1
Pages
19-24
Document Type
Article
EPub Date
2015/12/15
Status
Faculty
Facility
School of Medicine
Primary Department
General Pediatrics
PMID
DOI
10.1097/mpg.0000000000001072