Clinical and laboratory issues associated with persistent low-level elevations of hCG in a female of childbearing age
Clinica Chimica Acta
Persistent low-level elevations of serum concentrations of hCG in a non-pregnant female of childbearing age were investigated by a number of laboratory techniques including heterophile blocking reagents, polyethylene glycol precipitation, serial dilutions and hCG measurements on several different instrument/reagent systems. The results of these studies indicated that this patient had immunoreactive hCG in her serum that was not the intact hCG molecule but primarily the free beta-hCG subunit. Differential diagnoses are discussed along with recommendation for continued surveillance of serum hCG concentrations. (C) 2013 Elsevier B.V. All rights reserved.
Faculty; Northwell Researcher
School of Medicine; Northwell Health
Pathology and Laboratory Medicine
Obstetrics and Gynecology