Publication Date
2014
Journal Title
Front Neuroendocrinol
Abstract
Sex differences are prominent in mood and anxiety disorders and may provide a window into mechanisms of onset and maintenance of affective disturbances in both men and women. With the plethora of sex differences in brain structure, function, and stress responsivity, as well as differences in exposure to reproductive hormones, social expectations and experiences, the challenge is to understand which sex differences are relevant to affective illness. This review will focus on clinical aspects of sex differences in affective disorders including the emergence of sex differences across developmental stages and the impact of reproductive events. Biological, cultural, and experiential factors that may underlie sex differences in the phenomenology of mood and anxiety disorders are discussed. (C) 2014 Published by Elsevier Inc.
Volume Number
35
Issue Number
3
Pages
320-330
Document Type
Article
Status
Northwell Resident
Facility
Northwell Health
Primary Department
Psychiatry
PMID
DOI
10.1016/j.yfrne.2014.05.004