Title

Collaborative retrospective macula society study of photodynamic therapy for chronic central serous chorioretinopathy

Publication Date

January 2014

Journal Title

Ophthalmology

Abstract

PURPOSE: To assess the visual and anatomic outcomes of central serous chorioretinopathy (CSC) after verteporfin photodynamic therapy (PDT). DESIGN: Retrospective case series. PARTICIPANTS: Patients with CSC who underwent PDT. METHODS: Members of the Macula Society were surveyed to retrospectively collect data on PDT treatment for CSC. Patient demographic information, PDT treatment parameters, fluorescein angiographic information, optical coherence tomography (OCT) metrics, pre- and post-treatment visual acuity (VA), and adverse outcomes were collected online using standardized forms. MAIN OUTCOME MEASURES: Visual acuities over time and presence or absence of subretinal fluid (SRF). RESULTS: Data were submitted on 265 eyes of 237 patients with CSC with a mean age of 52 (standard deviation [+/- 11]) years; 61 were women (26%). Mean baseline logarithm of the minimum angle of resolution (logMAR) VA was 0.39+/-0.36 (20/50). Baseline VAs were >/=20/32 in 115 eyes (43%), 20/40 to 20/80 in 97 eyes (37%), and /=3 lines in <1%, 29%, and 48% of eyes with baseline VA >/=20/32, 20/40 to 20/80, and 0.01). Complications were rare: Retinal pigment epithelial atrophy was seen in 4% of patients, and acute severe visual decrease was seen in 1.5% of patients. CONCLUSIONS: Photodynamic therapy was associated with improved VA and resolution of SRF. Adverse side effects were rare.

Volume Number

121

Issue Number

5

Pages

1073-8

Document Type

Article

EPub Date

2014/01/21

Facility

Northwell Health

Primary Department

Ophthalmology

PMID

24439758

DOI

10.1016/j.ophtha.2013.11.040

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