Collaborative retrospective macula society study of photodynamic therapy for chronic central serous chorioretinopathy
Publication Date
2014
Journal Title
Ophthalmology
Abstract
PURPOSE: To assess the visual and anatomic outcomes of central serous chorioretinopathy (CSC) after verteporfin photodynamic therapy (PDT). DESIGN: Retrospective case series. PARTICIPANTS: Patients with CSC who underwent PDT. METHODS: Members of the Macula Society were surveyed to retrospectively collect data on PDT treatment for CSC. Patient demographic information, PDT treatment parameters, fluorescein angiographic information, optical coherence tomography (OCT) metrics, pre- and post-treatment visual acuity (VA), and adverse outcomes were collected online using standardized forms. MAIN OUTCOME MEASURES: Visual acuities over time and presence or absence of subretinal fluid (SRF). RESULTS: Data were submitted on 265 eyes of 237 patients with CSC with a mean age of 52 (standard deviation [+/- 11]) years; 61 were women (26%). Mean baseline logarithm of the minimum angle of resolution (logMAR) VA was 0.39+/-0.36 (20/50). Baseline VAs were >/=20/32 in 115 eyes (43%), 20/40 to 20/80 in 97 eyes (37%), and/=3 lines in/=20/32, 20/40 to 20/80, and0.01). Complications were rare: Retinal pigment epithelial atrophy was seen in 4% of patients, and acute severe visual decrease was seen in 1.5% of patients. CONCLUSIONS: Photodynamic therapy was associated with improved VA and resolution of SRF. Adverse side effects were rare.
Volume Number
121
Issue Number
5
Pages
1073-8
Document Type
Article
EPub Date
2014/01/21
Status
Northwell Researcher
Facility
Northwell Health
Primary Department
Ophthalmology
PMID
DOI
10.1016/j.ophtha.2013.11.040