Transfusion-transmitted babesiosis leading to severe hemolysis in two patients with sickle cell anemia
Pediatr Blood Cancer
© 2017 Wiley Periodicals, Inc. The intracellular parasites Babesia microti and Babesia duncani can be transmitted by blood transfusion and cause severe life-threatening hemolytic anemia in high-risk patients, including those with sickle cell disease. The rarity of the diagnosis, as well as its similar clinical presentation to delayed hemolytic transfusion reaction, may lead to a delay in diagnosis, as well as inappropriate treatment with steroids or other immunosuppressive agents. The morbidity caused by this disease in especially vulnerable populations justifies the need for a universal blood-screening program in endemic areas.
School of Medicine
Pathology and Laboratory Medicine