Transfusion-transmitted babesiosis leading to severe hemolysis in two patients with sickle cell anemia
Publication Date
2018
Journal Title
Pediatr Blood Cancer
Abstract
© 2017 Wiley Periodicals, Inc. The intracellular parasites Babesia microti and Babesia duncani can be transmitted by blood transfusion and cause severe life-threatening hemolytic anemia in high-risk patients, including those with sickle cell disease. The rarity of the diagnosis, as well as its similar clinical presentation to delayed hemolytic transfusion reaction, may lead to a delay in diagnosis, as well as inappropriate treatment with steroids or other immunosuppressive agents. The morbidity caused by this disease in especially vulnerable populations justifies the need for a universal blood-screening program in endemic areas.
Volume Number
65
Issue Number
1
Document Type
Article
Status
Faculty
Facility
School of Medicine
Primary Department
General Pediatrics
Additional Departments
Pathology and Laboratory Medicine
PMID
DOI
10.1002/pbc.26734