Transfusion-transmitted babesiosis leading to severe hemolysis in two patients with sickle cell anemia

Publication Date

2018

Journal Title

Pediatr Blood Cancer

Abstract

© 2017 Wiley Periodicals, Inc. The intracellular parasites Babesia microti and Babesia duncani can be transmitted by blood transfusion and cause severe life-threatening hemolytic anemia in high-risk patients, including those with sickle cell disease. The rarity of the diagnosis, as well as its similar clinical presentation to delayed hemolytic transfusion reaction, may lead to a delay in diagnosis, as well as inappropriate treatment with steroids or other immunosuppressive agents. The morbidity caused by this disease in especially vulnerable populations justifies the need for a universal blood-screening program in endemic areas.

Volume Number

65

Issue Number

1

Document Type

Article

Status

Faculty

Facility

School of Medicine

Primary Department

General Pediatrics

Additional Departments

Pathology and Laboratory Medicine

PMID

28766838

DOI

10.1002/pbc.26734

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