Publication Date
2014
Journal Title
Br J Cancer
Abstract
Background: Securing a diagnosis of ovarian cancer and establishing means to predict outcomes to therapeutics remain formidable clinical challenges. Early diagnosis is particularly important since survival rates are markedly improved if tumour is detected early. Methods: Comprehensive miRNA profiles were generated on presurgical plasma samples from 42 women with confirmed serous epithelial ovarian cancer, 36 women diagnosed with a benign neoplasm, and 23 comparably age-matched women with no known pelvic mass. Results: Twenty-two miRNAs were differentially expressed between healthy controls and the ovarian cancer group (P
Volume Number
110
Issue Number
4
Pages
976-983
Document Type
Article
EPub Date
2013/12/25
Status
Faculty, Northwell Researcher
Facility
School of Medicine; Northwell Health
Primary Department
Obstetrics and Gynecology
Additional Departments
Molecular Medicine
PMID
DOI
10.1038/bjc.2013.795