Expanding the genetics of huntingtonism
Publication Date
2014
Journal Title
Neurology
Abstract
The lines defining many clinical syndromes have become blurred. A patient presenting with what appears to be Parkinson disease may in fact have one of several genetic mutations (e.g., LRRK2, parkin), an atypical parkinsonian syndrome (e.g., multisystem atrophy, progressive supranuclear palsy), sporadic idiopathic Parkinson disease, or a number of other conditions. Conversely, known genetic mutations may have classical presentations, but they may also present with widely varying signs and symptoms.
Volume Number
82
Issue Number
4
Pages
286-287
Document Type
Article
EPub Date
2013/12/24
Status
Faculty
Facility
School of Medicine
Primary Department
Neurology
Additional Departments
Molecular Medicine
PMID
DOI
10.1212/wnl.0000000000000067