The Sphenopalatine Ganglion: Anatomy, Pathophysiology, and Therapeutic Targeting in Headache

Publication Date

2016

Journal Title

Headache

Abstract

The sphenopalatine ganglion (SPG) has attracted the interest of practitioners treating head and face pain for over a century because of its anatomical connections and role in the trigemino-autonomic reflex. In this review, we discuss the anatomy of the SPG, as well as what is known about its role in the pathophysiology of headache disorders, including cluster headache and migraine. We then address various therapies that target the SPG, including intranasal medication delivery, new SPG blocking catheter devices, neurostimulation, chemical neurolysis, and ablation procedures.

Volume Number

56

Issue Number

2

Pages

240-58

Document Type

Article

EPub Date

2015/12/01

Status

Faculty

Facility

School of Medicine

Primary Department

Neurology

PMID

26615983

DOI

10.1111/head.12729

Comments

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