Hypothalamic dysfunction without hamartomas causing gelastic seizures in optic nerve hypoplasia

Publication Date

2015

Journal Title

J Child Neurol

Abstract

This report describes gelastic seizures in patients with optic nerve hypoplasia and hypothalamic dysfunction without hypothalamic hamartoma. All participants (n = 4) from the optic nerve hypoplasia registry study at Children's Hospital Los Angeles presenting with gelastic seizures were included. The clinical and pathology characteristics include hypothalamic dysgenesis and dysfunction, but no hamartomas. Optic nerve hypoplasia is the only reported condition with gelastic seizures without hypothalamic hamartomas, suggesting that hypothalamic disorganization alone can cause gelastic seizures.

Volume Number

30

Issue Number

2

Pages

233-7

Document Type

Article

EPub Date

2014/04/05

Status

Northwell Researcher

Facility

Northwell Health

Primary Department

Ophthalmology

PMID

24700666

DOI

10.1177/0883073814527156

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