New insights into Stargardt disease with multimodal imaging
Publication Date
2015
Journal Title
Ophthalmic Surg Lasers Imaging Retina
Abstract
A 20-year-old woman with bilateral mild blurring of vision presented with a bull's eye maculopathy and was diagnosed with Stargardt disease, confirmed with genetic testing. The authors present several novel multimodal imaging findings including multicolor and multi-spectral imaging that enhanced visualization of perifoveal flecks, fundus autofluorescence that revealed both perifoveal and perimacular rings of hyperautofluorescence, adaptive optics imaging that revealed unprecedented visualization of cones at the fovea due to decreased cone density, and spectral-domain optical coherence tomography that identified thickening and increased hyperreflectivity of the external limiting membrane as a possible transient biomarker of early Stargardt disease.
Volume Number
46
Issue Number
2
Pages
257-61
Document Type
Article
EPub Date
2015/02/24
Status
Northwell Researcher
Facility
Northwell Health
Primary Department
Ophthalmology
PMID
DOI
10.3928/23258160-20150213-09
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