Is there a need for an alternative in the era of novel anticoagulants?

Publication Date

2015

Journal Title

Expert Rev Cardiovasc Ther

Abstract

With the development of the new direct oral anticoagulants, many of the unmet needs of the vitamin K antagonists were fulfilled, such as the absence of dietary interactions, few drug interactions, predictable effects and no need for monitoring. However, growing experience with the direct oral anticoagulants indicates there is still room for improvement. Developing antithrombotic agents that optimize their antithrombotic effect while producing little or no risk of bleeding is a long sought after goal. This and other enhanced attributes of candidate drugs are on the horizon.

Volume Number

13

Issue Number

9

Pages

967-70

Document Type

Article

EPub Date

2015/07/21

Status

Faculty

Facility

School of Medicine

Primary Department

General Internal Medicine

PMID

26189357

DOI

10.1586/14779072.2015.1069707

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