Antiresorptive Therapies for Osteoporosis
Publication Date
2015
Journal Title
Oral Maxillofac Surg Clin North Am
Abstract
Osteoporosis is a disease of low bone density, translating to increased fragility and risk for fracture. It is a significant public health problem that is widely undertreated, despite the many options of treatment available. Among these, the most effective are the antiresorptive medications, such as bisphosphonates. There is an abundance of evidence about the efficacy and safety profile of these medications. However, there is mounting evidence that, after 10 years on treatment with a bisphosphonate, patients are at a higher risk of developing some of the serious side effects of atypical femur fractures and osteonecrosis of the jaw.
Volume Number
27
Issue Number
4
Pages
555-60
Document Type
Article
EPub Date
2015/09/29
Status
Faculty
Facility
School of Medicine
Primary Department
Endocrinology, Diabetes, and Metabolism
PMID
DOI
10.1016/j.coms.2015.07.001