Antiresorptive Therapies for Osteoporosis

Publication Date

2015

Journal Title

Oral Maxillofac Surg Clin North Am

Abstract

Osteoporosis is a disease of low bone density, translating to increased fragility and risk for fracture. It is a significant public health problem that is widely undertreated, despite the many options of treatment available. Among these, the most effective are the antiresorptive medications, such as bisphosphonates. There is an abundance of evidence about the efficacy and safety profile of these medications. However, there is mounting evidence that, after 10 years on treatment with a bisphosphonate, patients are at a higher risk of developing some of the serious side effects of atypical femur fractures and osteonecrosis of the jaw.

Volume Number

27

Issue Number

4

Pages

555-60

Document Type

Article

EPub Date

2015/09/29

Status

Faculty

Facility

School of Medicine

Primary Department

Endocrinology, Diabetes, and Metabolism

PMID

26412797

DOI

10.1016/j.coms.2015.07.001

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