Publication Date

2014

Journal Title

Lupus Sci Med

Abstract

OBJECTIVE: Correlates of systemic lupus erythematosus (SLE) Responder Index (SRI) response with clinical trial end points were examined using pooled data from the Study of Belimumab in Subjects with SLE (BLISS) trials (N=1684). METHODS: Changes in clinical, laboratory and health-related quality of life measures from baseline at 52 weeks were compared between SRI responders (n=761) and non-responders (n=923). RESULTS: More SRI responders than non-responders had >/=4-point (100% vs 3.8%) and >/=7-point (40.3% vs 1.3%) Safety of Estrogens in Lupus Erythematosus National Assessment-Systemic Lupus Erythematosus Disease Activity Index reductions, no new British Isles Lupus Assessment Group (BILAG) A and7.5 mg/d to7.5 mg/d (4.1% vs 21.3%; all p

Volume Number

1

Issue Number

1

Pages

e000031

Document Type

Article

EPub Date

2014/11/15

Status

Faculty

Facility

School of Medicine

Primary Department

Rheumatology

PMID

25396065

DOI

10.1136/lupus-2014-000031


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