Glomerular Diseases Associated With Cancer, Chemotherapy, and Hematopoietic Stem Cell Transplantation
Publication Date
2014
Journal Title
Adv Chronic Kidney Dis
Abstract
Many solid and hematological malignancies have been associated with different glomerular diseases. Several case reports and case series of cancer-associated glomerular diseases have shown that treating the cancer may lead to resolution of the glomerular process. Hence, knowledge and approach to cancer-associated glomerular diseases is important for both the caring nephrologists and the cancer specialists. While membranous nephropathy has been classically associated with solid malignancies, minimal change disease has been commonly described with hematologic malignancies, especially non-Hodgkin's lymphoma. Membranoproliferative glomerulonephritis is increasingly being recognized to be associated with chronic hematologic malignancies such as chronic lymphocytic leukemia. In this article, we review various cancer-associated glomerular diseases and their pathogenesis as well as principles of treatment. In addition, we also review glomerular diseases seen after chemotherapy and hematopoietic stem cell transplantation. (C) 2014 by the National Kidney Foundation, Inc. All rights reserved.
Volume Number
21
Issue Number
1
Pages
48-55
Document Type
Article
EPub Date
2013/12/24
Status
Faculty, Northwell Researcher
Facility
School of Medicine; Northwell Health
Primary Department
Nephrology
Additional Departments
General Internal Medicine
PMID
DOI
10.1053/j.ackd.2013.08.003