Glomerular Diseases Associated With Cancer, Chemotherapy, and Hematopoietic Stem Cell Transplantation

Publication Date

2014

Journal Title

Adv Chronic Kidney Dis

Abstract

Many solid and hematological malignancies have been associated with different glomerular diseases. Several case reports and case series of cancer-associated glomerular diseases have shown that treating the cancer may lead to resolution of the glomerular process. Hence, knowledge and approach to cancer-associated glomerular diseases is important for both the caring nephrologists and the cancer specialists. While membranous nephropathy has been classically associated with solid malignancies, minimal change disease has been commonly described with hematologic malignancies, especially non-Hodgkin's lymphoma. Membranoproliferative glomerulonephritis is increasingly being recognized to be associated with chronic hematologic malignancies such as chronic lymphocytic leukemia. In this article, we review various cancer-associated glomerular diseases and their pathogenesis as well as principles of treatment. In addition, we also review glomerular diseases seen after chemotherapy and hematopoietic stem cell transplantation. (C) 2014 by the National Kidney Foundation, Inc. All rights reserved.

Volume Number

21

Issue Number

1

Pages

48-55

Document Type

Article

EPub Date

2013/12/24

Status

Faculty, Northwell Researcher

Facility

School of Medicine; Northwell Health

Primary Department

Nephrology

Additional Departments

General Internal Medicine

PMID

24359986

DOI

10.1053/j.ackd.2013.08.003

For the public and Northwell Health campuses

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