STABLE Results: Warfarin Home Monitoring Achieves Excellent INR Control

Publication Date

2014

Journal Title

Am J Manag Care

Abstract

Objectives: Point-of-care, home international normalized ratio (INR) monitoring (patient self-testing, or PST) provides an opportunity to optimize warfarin therapy as demonstrated in randomized trials.This study sought to determine the quality of warfarin therapy as determined by time in therapeutic INR range (TTR) in patients who perform home monitoring outside of a clinical trial setting. Study Design: Retrospective analysis. Methods: The data base of an independent diagnostic testing facility was retrospectively queried over a 2.5-year period (January 2008-June 2011) and patientTTR was analyzed based on frequency of testing, age, gender, indication for therapy, duration of therapy, and critical value occurrence. Results: A total of 29,457 patients with multiple indications for warfarin therapy comprised the database.The mean TTR for the entire group was 69.7%, with weekly testers achieving a TTR of 74% versus 68.9% for variable testers (testing every 2-4 weeks)(P5.0) than did variable testers. Conclusions: Point-of-care patient self-testing at home achieves high-quality warfarin therapy outside of clinical trials and compares favorably with the results achieved in randomized trials or in anticoagulation clinic settings.

Volume Number

20

Issue Number

3

Pages

202-209

Document Type

Article

Status

Faculty

Facility

School of Medicine

Primary Department

General Internal Medicine

PMID

24884750

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