Title
Regulating innate immunity with dopamine and electroacupuncture
Publication Date
2014
Journal Title
Nat Med
Abstract
Neural circuits are able to modulate immune responses by detecting inflammatory mediators and relaying signals back to the immune system. Here, in a mouse model of sepsis, the authors show that the immune responses can be modulated by electroacupuncture, which stimulates a neural circuit that results in the release of dopamine. The mechanism, like the inflammatory reflex, is neither sympathetic nor parasympathetic. Their results show a potential way forward in developing therapies for sepsis in dopamine agonists (pages 291-295).
Volume Number
20
Issue Number
3
Pages
239-241
Document Type
Article
EPub Date
2014/03/08
Status
Faculty
Facility
School of Medicine
Primary Department
Molecular Medicine
Additional Departments
Neurosurgery
PMID
DOI
10.1038/nm.3501