The Genotype and Phenotype (GaP) registry: a living biobank for the analysis of quantitative traits

Publication Date

2015

Journal Title

Immunol Res

Abstract

We describe the development of the Genotype and Phenotype (GaP) Registry, a living biobank of normal volunteers who are genotyped for genetic markers related to human disease. Participants in the GaP can be recalled for hypothesis driven study of disease associated genetic variants. The GaP has facilitated functional studies of several autoimmune disease associated loci including Csk, Blk, PDRM1 (Blimp-1) and PTPN22. It is likely that expansion of such living biobank registries will play an important role in studying and understanding the function of disease associated alleles in complex disease.

Volume Number

63

Issue Number

1-3

Pages

107-12

Document Type

Article

EPub Date

2015/10/16

Status

Faculty, Northwell Researcher

Facility

School of Medicine; Northwell Health

Primary Department

Molecular Medicine

Additional Departments

General Internal Medicine

PMID

26467974

DOI

10.1007/s12026-015-8711-8

For the public and Northwell Health campuses

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