Activity restriction and risk of preterm delivery

Publication Date

2018

Journal Title

J Matern Fetal Neonatal Med

Abstract

© 2017 Informa UK Limited, trading as Taylor & Francis Group. Purpose: We sought to determine whether activity restriction (AR) in a cohort of women at high risk for preterm delivery is associated with the risk of preterm delivery. Materials and methods: This is a secondary analysis of the Maternal-Fetal Medicine Units MFMU’s Preterm Prediction Study; a multicenter prospective cohort study designed to identify risk factors of preterm birth (PTB). The study group consisted of women with a singleton gestation that at their first study visit (23–24 weeks) had at least one of the following criteria: patient reported contractions, severe back pain, a cervical length <15 >mm, spotting, protruding membranes, or positive fetal fibronectin. Women were assessed for AR at a 27- to 29-week study visit. Associations between AR and preterm delivery (<37 >weeks) were examined through logistic regression models before and after adjustment for confounders. Results: Of the 1086 women that met the inclusion criteria, 16.5% (n = 179) delivered preterm. In this cohort, 9.7% (n = 105) of women were recommended AR, with 37.1% (n = 39) having a PTB. In the group not recommended AR (n = 981), 14.3% (n = 140) delivered preterm. Conclusion: In this cohort of women at high risk for PTB, activity restriction was associated with an increased risk of PTB. The use of AR in this population should be discouraged.

Volume Number

31

Issue Number

16

Pages

2136 - 2140

Document Type

Article

Status

Faculty

Facility

School of Medicine

Primary Department

Obstetrics and Gynecology

PMID

28573877

DOI

10.1080/14767058.2017.1337738

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