Metabolic obesity phenotypes and risk of colorectal cancer in postmenopausal women.

Publication Date

2018

Journal Title

Int J Cancer

Abstract

Obesity has been postulated to increase the risk of colorectal cancer by mechanisms involving insulin resistance and the metabolic syndrome. We examined the associations of body mass index (BMI), waist circumference, the metabolic syndrome, metabolic obesity phenotypes and homeostasis model-insulin resistance (HOMA-IR-a marker of insulin resistance) with risk of colorectal cancer in over 21,000 women in the Women's Health Initiative CVD Biomarkers subcohort. Women were cross-classified by BMI (18.5-

Volume Number

143

Issue Number

3

Pages

543-551

Document Type

Article

Status

Faculty

Facility

School of Medicine

Primary Department

Occupational Medicine, Epidemiology, and Prevention

PMID

29488210

DOI

10.1002/ijc.31345

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