Age-associated B cells acquire a new wrinkle news-and-views

Publication Date

2018

Journal Title

Nat Immunol

Abstract

© 2018 The Author(s). SWAP-70 and DEF6 prevent the cytokine IL-21-induced transcription factor IRF5 from binding to DNA and recruiting the transcription factor T-bet and thereby diminish the activation of age-associated B cells.

Volume Number

19

Issue Number

4

Pages

317 - 318

Document Type

Article

Status

Faculty, Northwell Researcher

Facility

School of Medicine; Northwell Health

Primary Department

Molecular Medicine

Additional Departments

General Internal Medicine

PMID

29563629

DOI

10.1038/s41590-018-0072-8

For the public and Northwell Health campuses

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