Publication Date

2018

Journal Title

Small GTPases

Abstract

© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group © 2017, © Lionel Blanc and Michel Vidal. In the last two decades, extracellular vesicle-mediated communication between cells has become a major field in cell biology. However, the function of extracellular vesicles is far from clear, especially due to the disparity of released vesicles by cells. Basically, one must consider vesicles budding from the cell plasma membrane (ectosomes) and vesicles released upon fusion of an endosomal multivesicular compartment (exosomes). Moreover, even for exosomes, we report and discuss here the possibility that different routes regulated by specific Rab GTPases might produce exosomes having various biologic functions.

Volume Number

9

Issue Number

1-2

Pages

95 - 106

Document Type

Article

Status

Faculty

Facility

School of Medicine

Primary Department

Molecular Medicine

Additional Departments

General Pediatrics

PMID

28135905

DOI

10.1080/21541248.2016.1264352


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