Preliminary findings of altered functional connectivity of the default mode network linked to functional outcomes one year after pediatric traumatic brain injury

Authors

J. A. Stephens
C. F. Salorio
A. D. Barber, Zucker School of Medicine at Hofstra/Northwell
S. R. Risen
S. H. Mostofsky
S. J. Suskauer

Publication Date

2018

Journal Title

Dev Neurorehabil

Abstract

© 2018, © 2018 Taylor & Francis. Purpose and Method: This study examined functional connectivity of the default mode network (DMN) and examined brain–behavior relationships in a pilot cohort of children with chronic mild to moderate traumatic brain injury (TBI). Results: Compared to uninjured peers, children with TBI demonstrated less anti-correlated functional connectivity between DMN and right Brodmann Area 40 (BA 40). In children with TBI, more anomalous less anti-correlated) connectivity between DMN and right BA 40 was linked to poorer performance on response inhibition tasks. Conclusion: Collectively, these preliminary findings suggest that functional connectivity between DMN and BA 40 may relate to longterm functional outcomes in chronic pediatric TBI.

Volume Number

21

Issue Number

7

Pages

423 - 430

Document Type

Article

Status

Faculty

Facility

School of Medicine

Primary Department

Psychiatry

PMID

28692408

DOI

10.1080/17518423.2017.1338777