Economic analysis of rapid multiplex polymerase chain reaction testing for meningitis/encephalitis in pediatric patients
Publication Date
2018
Journal Title
Future Microbiol
Abstract
© 2018 Future Medicine Ltd. Aim: We assessed the possible economic impact of a rapid test in pediatric patients with suspected community-acquired meningitis/encephalitis. Materials & methods: Modeling simulated diagnosis, clinical decisions, resource use/costs of standard of care (SOC) and two cerebrospinal fluid testing strategies using FilmArray®(FA), a US FDA-cleared system that provides results in approximately 1 h. Results: Pathogens detected by FA caused approximately 75% of cases, 97% of which would be accurately diagnosed with FA. Mean cost/case ranged from 17,599 to 22,025. Syndromic testing is less expensive than SOC. Testing all suspected cases yielded greater savings (3481/case) than testing only those with abnormal cerebrospinal fluid (2157/case). Conclusion: Greater economic benefits are achievable with syndromic testing of all cases, rather than SOC or targeted syndromic testing.
Volume Number
13
Issue Number
6
Pages
617 - 629
Document Type
Article
Status
Faculty
Facility
School of Medicine
Primary Department
Pathology and Laboratory Medicine
Additional Departments
Molecular Medicine
PMID
DOI
10.2217/fmb-2017-0238
This document is currently not available here.
COinS
Comments
Hofstra Northwell School of Medicine and Northwell Health currently do not subscribe to this title. If you are an affiliate and would like to access the full text please request it via interlibrary loan via Hofstra Northwell School of Medicine ILL (faculty and students only) or Northwell Health ILL