Sex differences in the treatment and outcomes of patients hospitalized with ST-elevation myocardial infarction
Publication Date
2019
Journal Title
Catheter Cardiovasc Interv
Abstract
© 2019 Wiley Periodicals, Inc. Objectives: To compare mortality for women and men hospitalized with ST-elevation myocardial infarction (STEMI) by age and revascularization status. Background: There is little information on the mortality of men and women not undergoing revascularization, and the impact of age on relative male–female mortality needs to be revisited. Methods and results: An observational database of 23,809 patients with STEMI presenting at nonfederal New York State hospitals between 2013 and 2015 was used to compare risk-adjusted inhospital/30-day mortality for women and men and to explore the impact of age on those differences. Women had significantly higher mortality than men overall (adjusted odds ratio [AOR] = 1.15, 95% CI [1.04, 1.28]), and among patients aged 65 and older. Women had lower revascularization rates in general (AOR = 0.64 [0.59, 0.69]) and for all age groups. Among revascularized STEMI patients, women overall (AOR = 1.30 [1.10, 1.53]) and over 65 had higher mortality than men. Among patients not revascularized, women between the ages of 45 and 64 had lower mortality (AOR = 0.68 [0.48, 0.97]). Conclusions: Women with STEMI, and especially older women, had higher inhospital/30-day mortality rates than their male counterparts. Women had higher mortality among revascularized patients, but not among patients who were not revascularized.
Document Type
Article
Status
Faculty
Facility
School of Medicine
Primary Department
Cardiology
Additional Departments
General Internal Medicine
PMID
DOI
10.1002/ccd.28286