Potential for Donation after Circulatory Death heart transplantation in the United States: Retrospective analysis of a limited UNOS dataset.
Publication Date
2019
Journal Title
Am J Transplant
Abstract
Donation After Circulatory Death (DCD) is an alternative to Donation after Brain Death (DBD), and is a growing strategy for organ procurement in the United States (US). The purpose of this analysis was to review the number and quality of hearts in one United Network for Organ Sharing (UNOS) Region that were not utilized as a potential consequence of non-heart DCD donation. We retrospectively identified all successful US DCD solid organ donors from 1/2011 - 3/1/2017, defined an ideal heart donor by age and left ventricular ejection fraction, and then reviewed the donor charts of unused hearts in New York and Vermont (UNOS Region 9). Of 8302 successful DCD donors across the US, 5033 (61%) were between 18-49 years of age, 872 had a screening echocardiogram, with 573 (66%) measuring an EF > 50%. Of these 573 potential donors, 44 (7.7%) were from Region 9. Detailed donor chart review identified 36 ideal heart donors, 24 (66.7%) with anoxic brain injury. Trends in Region 9 DCD donation increased from 4 unused hearts in 2011, to 13 in 2016. In the context of severe organ scarcity, these data indicated that implementation of DCD heart transplantation in the US would improve overall donation rates and in particular, allow utilization of these ideal donor hearts.
Document Type
Article
Status
Faculty
Facility
School of Medicine
Primary Department
Cardiology
PMID
DOI
10.1111/ajt.15597